Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tex11tm1Jw mutation
(0 available);
any
Tex11 mutation
(20 available)
Tmem163Tg(ACTB-cre)2Mrt mutation
(3 available);
any
Tmem163 mutation
(35 available)
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reproductive system
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• pachytene oocytes contain asynapsed chromosomes unlike in wild-type mice
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cellular
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• pachytene oocytes contain asynapsed chromosomes unlike in wild-type mice
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tex11tm1Jw mutation
(0 available);
any
Tex11 mutation
(20 available)
Tmem163Tg(ACTB-cre)2Mrt mutation
(3 available);
any
Tmem163 mutation
(35 available)
|
|
|
reproductive system
|
• some spermatocytes exhibit desynapsis at diplotene due to defective crossover formation during pachytene
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• during anaphase, a few chromatin masses migrate ahead or lag behind the two major chromatin masses unlike in wild-type spermatocytes
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• sperm cells undergo increased apoptosis compared to in wild-type mice during pachytene and anaphase I
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• testes weight is 50% of wild-type
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endocrine/exocrine glands
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• testes weight is 50% of wild-type
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cellular
|
• some spermatocytes exhibit desynapsis at diplotene due to defective crossover formation during pachytene
|
|
• during anaphase, a few chromatin masses migrate ahead or lag behind the two major chromatin masses unlike in wild-type spermatocytes
|
|
• sperm cells undergo increased apoptosis compared to in wild-type mice during pachytene and anaphase I
|