All Phenotypes Del(16Cbr1-Fam3b)1Rhr MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Del(16Cbr1-Fam3b)1Rhr
deletion, chr 16, R H Reeves 1
MGI:3487281

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Del(16Cbr1-Fam3b)1Rhr/+	involves: 129S6/SvEvTac * C57BL/6	MGI:3718055
cx2	Del(16Cbr1-Fam3b)1Rhr/Dp(16Lipi-Zbtb21)1Yey	involves: 129S6/SvEvTac * 129S7/SvEvBrd * C3H/HeJ * C3H/HeSnJ * C57BL/6 * C57BL/LiA	MGI:5690021
cx3	Ts(17¹⁶)65Dn/Del(16Cbr1-Fam3b)1Rhr	involves: 129S6/SvEvTac * C57BL/6 * DBA/2J	MGI:3718058

Allelic Composition	Del(16Cbr1-Fam3b)1Rhr/+
Genetic Background	involves: 129S6/SvEvTac * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(16Cbr1-Fam3b)1Rhr mutation (1 available); any Del(16Cbr1-Fam3b)1Rhr mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

infertility ( J:121764 )

• mice cannot inbred

nervous system

increased brain size ( J:121764 )

• brain size is slightly larger than in control mice

decreased hippocampus volume ( J:121764 )

• hippocampus volume is 51% of that in control mice

increased Purkinje cell number ( J:121764 )

• Purkinje cell density is increased to 116% of that in control mice

increased cerebellar granule cell number ( J:121764 )

• granule cell density is increased to 115% of that in control mice

enlarged cerebellum ( J:121764 )

• cerebellum size is 104% larger than in controls

behavior/neurological

behavior/neurological phenotype ( J:121764 )

N	• mice perform similar to control mice in a Morris water maze mice perform similar to control mice in a Morris water maze

growth/size/body

decreased body size ( J:93223 , J:121764 )

• mice are smaller at birth (J:93223)

• mice are smaller at birth (J:121764)

Allelic Composition	Del(16Cbr1-Fam3b)1Rhr/Dp(16Lipi-Zbtb21)1Yey
Genetic Background	involves: 129S6/SvEvTac * 129S7/SvEvBrd * C3H/HeJ * C3H/HeSnJ * C57BL/6 * C57BL/LiA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(16Cbr1-Fam3b)1Rhr mutation (1 available); any Del(16Cbr1-Fam3b)1Rhr mutation (1 available)
Dp(16Lipi-Zbtb21)1Yey mutation (3 available); any Dp(16Lipi-Zbtb21)1Yey mutation (3 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

impaired contextual conditioning behavior ( J:224899 )

• mice exhibit decreased freezing behavior in contextual fear-conditioning test as compared to wild type

Allelic Composition	Ts(17¹⁶)65Dn/Del(16Cbr1-Fam3b)1Rhr
Genetic Background	involves: 129S6/SvEvTac * C57BL/6 * DBA/2J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(16Cbr1-Fam3b)1Rhr mutation (1 available); any Del(16Cbr1-Fam3b)1Rhr mutation (1 available)
Ts(17¹⁶)65Dn mutation (2 available); any Ts(17¹⁶)65Dn mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:121764 )

N	• mice perform similar to control mice in a Morris water maze with a visible or hidden platform

craniofacial

abnormal craniofacial morphology ( J:93223 )

• mice have craniofacial dysmorpholgy that is similar to that seen in Ts(17¹⁶)65Dn mice

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