All Phenotypes Srgn<tm1Mabr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Srgn^tm1Mabr
targeted mutation 1, Magnus Abrink
MGI:3057187

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Srgn^tm1Mabr/Srgn^tm1Mabr	involves: 129X1/SvJ	MGI:3057334

Allelic Composition	Srgn^tm1Mabr/Srgn^tm1Mabr
Genetic Background	involves: 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srgn^tm1Mabr mutation (0 available); any Srgn mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Srgn^tm1Mabr/Srgn^tm1Mabr peritoneal mast cells contain large empty vesicles

hematopoietic system

abnormal mast cell morphology ( J:93338 )

• peritoneal mast cells contain large empty vesicles

• granule formation is readily stimulated but granules do not mature

decreased mast cell number ( J:93338 )

immune system

abnormal mast cell morphology ( J:93338 )

• peritoneal mast cells contain large empty vesicles

• granule formation is readily stimulated but granules do not mature

decreased mast cell number ( J:93338 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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