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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Myf6tm1Tajb
targeted mutation 1, Shahragim Tajbakhsh
MGI:3055352
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Abl1tm1Gcos/Abl1+
Myf5tm2Tajb/Myf5tm2Tajb
Myf6tm1Tajb/Myf6tm1Tajb
Myod1tm2.1(icre)Glh/Myod1+ 		involves: 129S * 129X1/SvJ * C57BL/6J MGI:4939891
cx2
 		Myf5tm2Tajb/Myf5tm2Tajb
Myf6tm1Tajb/Myf6tm1Tajb 		involves: 129S2/SvPas MGI:3850158
cx3
 		Myf5tm2Tajb/Myf5tm2Tajb
Myf6tm1Tajb/Myf6+ 		involves: 129S2/SvPas * BALB/c * C57BL/6 MGI:3718095


Genotype
MGI:4939891
cn1
Allelic
Composition		 Abl1tm1Gcos/Abl1+
Myf5tm2Tajb/Myf5tm2Tajb
Myf6tm1Tajb/Myf6tm1Tajb
Myod1tm2.1(icre)Glh/Myod1+
Genetic
Background		 involves: 129S * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abl1tm1Gcos mutation (0 available); any Abl1 mutation (92 available)
Myf5tm2Tajb mutation (0 available); any Myf5 mutation (17 available)
Myf6tm1Tajb mutation (0 available); any Myf6 mutation (19 available)
Myod1tm2.1(icre)Glh mutation (1 available); any Myod1 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
abnormal myogenesis ( J:168843 )
• skeletal myogenesis is not suppressed by genotoxins unlike in wild-type mice

homeostasis/metabolism
decreased physiological sensitivity to xenobiotic ( J:168843 )
• skeletal myogenesis is not suppressed by genotoxins unlike in wild-type mice




Genotype
MGI:3850158
cx2
Allelic
Composition		 Myf5tm2Tajb/Myf5tm2Tajb
Myf6tm1Tajb/Myf6tm1Tajb
Genetic
Background		 involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myf5tm2Tajb mutation (0 available); any Myf5 mutation (17 available)
Myf6tm1Tajb mutation (0 available); any Myf6 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
abnormal extraocular muscle morphology ( J:150130 )
• mice phenocopy Myf5tm1Pas homozygotes
abnormal eye muscle development ( J:150130 )
• mice phenocopy Myf5tm1Pas homozygotes

vision/eye
abnormal extraocular muscle morphology ( J:150130 )
• mice phenocopy Myf5tm1Pas homozygotes
abnormal eye muscle development ( J:150130 )
• mice phenocopy Myf5tm1Pas homozygotes




Genotype
MGI:3718095
cx3
Allelic
Composition		 Myf5tm2Tajb/Myf5tm2Tajb
Myf6tm1Tajb/Myf6+
Genetic
Background		 involves: 129S2/SvPas * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myf5tm2Tajb mutation (0 available); any Myf5 mutation (17 available)
Myf6tm1Tajb mutation (0 available); any Myf6 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
abnormal muscle development ( J:92799 )
• Myod expression is half that seen in wild-type mice
• before E10.5, markers of muscle differentiation are lacking




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory