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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Or10j5tm2Mom
targeted mutation 2, Peter Mombaerts
MGI:3051333
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Or10j5tm2Mom/Or10j5+
Tg(Olfr16*,taulacZ)7Mom/? 		involves: 129 * C57BL/6 MGI:3718358
cx2
 		Adcy3tm1Drs/Adcy3tm1Drs
Or10j5tm2Mom/Or10j5+ 		involves: 129X1/SvJ * C57BL/6 MGI:3714867


Genotype
MGI:3718358
cx1
Allelic
Composition		 Or10j5tm2Mom/Or10j5+
Tg(Olfr16*,taulacZ)7Mom/?
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or10j5tm2Mom mutation (2 available); any Or10j5 mutation (46 available)
Tg(Olfr16*,taulacZ)7Mom mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory sensory neuron morphology ( J:78878 )
• several Olfr16+ olfactory neuron axons are mistargeted
abnormal olfactory bulb morphology ( J:78878 )
• ectopic glomeruli form and are aberrantly innervated

craniofacial
abnormal olfactory sensory neuron morphology ( J:78878 )
• several Olfr16+ olfactory neuron axons are mistargeted

respiratory system
abnormal olfactory sensory neuron morphology ( J:78878 )
• several Olfr16+ olfactory neuron axons are mistargeted

taste/olfaction
abnormal olfactory sensory neuron morphology ( J:78878 )
• several Olfr16+ olfactory neuron axons are mistargeted

growth/size/body
abnormal olfactory sensory neuron morphology ( J:78878 )
• several Olfr16+ olfactory neuron axons are mistargeted




Genotype
MGI:3714867
cx2
Allelic
Composition		 Adcy3tm1Drs/Adcy3tm1Drs
Or10j5tm2Mom/Or10j5+
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adcy3tm1Drs mutation (0 available); any Adcy3 mutation (42 available)
Or10j5tm2Mom mutation (2 available); any Or10j5 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory bulb morphology ( J:122528 )
• glomeruli structure is irregular




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory