All Phenotypes Usp39<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Usp39⁺
wild type
MGI:3049812

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Usp39^{tm1b(EUCOMM)Hmgu}/Usp39⁺	C57BL/6N-Usp39^{tm1b(EUCOMM)Hmgu}/Nju	MGI:5797904
cx2	Grhl3^tm1(cre)Cgh/Grhl3⁺ Usp39^em1Imat/Usp39⁺	involves: 129P2/OlaHsd * CD-1	MGI:7287462
cx3	Grhl3^tm1(cre)Cgh/Grhl3^tm1(cre)Cgh Usp39^em1Imat/Usp39⁺	involves: 129P2/OlaHsd * CD-1	MGI:7287463
cx4	Usp39^em1Imat/Usp39⁺ Vangl2^Lp/Vangl2^Lp	involves: A * CD-1	MGI:7287423

Allelic Composition	Usp39^{tm1b(EUCOMM)Hmgu}/Usp39⁺
Genetic Background	C57BL/6N-Usp39^{tm1b(EUCOMM)Hmgu}/Nju
Cell Lines	HEPD0763_5_C04

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Usp39^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Usp39 mutation (26 available)

Data Sources

IMPC Data for Usp39

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - MARC

integument

abnormal coat/hair pigmentation ( J:211773 )

IMPC - MARC

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

IMPC - MARC

Allelic Composition	Grhl3^tm1(cre)Cgh/Grhl3⁺ Usp39^em1Imat/Usp39⁺
Genetic Background	involves: 129P2/OlaHsd * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grhl3^tm1(cre)Cgh mutation (1 available); any Grhl3 mutation (53 available)
Usp39^em1Imat mutation (0 available); any Usp39 mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal hair growth ( J:324183 )

• hair fails to grow on thickened scaly skin

scaly skin ( J:324183 )

• thickened scaly skin in some mice

thick skin ( J:324183 )

• thickened scaly skin in some mice

Allelic Composition	Grhl3^tm1(cre)Cgh/Grhl3^tm1(cre)Cgh Usp39^em1Imat/Usp39⁺
Genetic Background	involves: 129P2/OlaHsd * CD-1

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

failure of eyelid fusion ( J:324183 )

• at increased frequency compared with Grhl3^tm1(cre)Cgh homozygotes at E15.5

Allelic Composition	Usp39^em1Imat/Usp39⁺ Vangl2^Lp/Vangl2^Lp
Genetic Background	involves: A * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Usp39^em1Imat mutation (0 available); any Usp39 mutation (26 available)
Vangl2^Lp mutation (2 available); any Vangl2 mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

short rostral-caudal axis ( J:324183 )

• shorter than in Vangl2^Lp homozygotes

limbs/digits/tail

abnormal limb development ( J:324183 )

• precocious hindlimb induction

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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