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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dact1+
wild type
MGI:3048281
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Dact1tm1.1Bnrc/Dact1+
Vangl2Lp/Vangl2+
B6.Cg-Vangl2Lp Dact1tm1.1Bnrc MGI:4360076
cx2
Dact1tm1.1Bnrc/Dact1+
Vangl2Lp-m1Jus/Vangl2+
involves: 101/Rl * 129 * C3H/Rl * C57BL/6 MGI:4360080
cx3
Dact1tm1.1Bnrc/Dact1+
Sestd1tm1.1Bnrc/Sestd1tm1.1Bnrc
involves: 129S6/SvEvTac * C57BL/6NCr MGI:5520976


Genotype
MGI:4360076
cx1
Allelic
Composition
Dact1tm1.1Bnrc/Dact1+
Vangl2Lp/Vangl2+
Genetic
Background
B6.Cg-Vangl2Lp Dact1tm1.1Bnrc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dact1tm1.1Bnrc mutation (0 available); any Dact1 mutation (18 available)
Vangl2Lp mutation (2 available); any Vangl2 mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• penetrance of the loop tail phenotype is decreased to less than 65% compared to greater than 80% in Vangl2 single heterozygotes




Genotype
MGI:4360080
cx2
Allelic
Composition
Dact1tm1.1Bnrc/Dact1+
Vangl2Lp-m1Jus/Vangl2+
Genetic
Background
involves: 101/Rl * 129 * C3H/Rl * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dact1tm1.1Bnrc mutation (0 available); any Dact1 mutation (18 available)
Vangl2Lp-m1Jus mutation (1 available); any Vangl2 mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• penetrance of the loop tail phenotype is decreased to less than 65% compared to greater than 80% in Vangl2 single heterozygotes




Genotype
MGI:5520976
cx3
Allelic
Composition
Dact1tm1.1Bnrc/Dact1+
Sestd1tm1.1Bnrc/Sestd1tm1.1Bnrc
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6NCr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dact1tm1.1Bnrc mutation (0 available); any Dact1 mutation (18 available)
Sestd1tm1.1Bnrc mutation (0 available); any Sestd1 mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system

limbs/digits/tail





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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory