All Phenotypes Dnai7<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dnai7⁺
wild type
MGI:3048108

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Dnai7^{Gt(VICTR21)709Lex}/Dnai7⁺	involves: 129S5/SvEvBrd	MGI:3689220

Allelic Composition	Dnai7^{Gt(VICTR21)709Lex}/Dnai7⁺
Genetic Background	involves: 129S5/SvEvBrd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnai7^{Gt(VICTR21)709Lex} mutation (0 available); any Dnai7 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased incidence of tumors by chemical induction ( J:111629 )

• 3X more tumors/mouse after treatment with urethane than seen in C57BL/6J (resistant) controls

increased lung adenocarcinoma incidence ( J:111629 )

• 16.8% of mice develop lung adenocarcenomas

homeostasis/metabolism

increased incidence of tumors by chemical induction ( J:111629 )

• 3X more tumors/mouse after treatment with urethane than seen in C57BL/6J (resistant) controls

respiratory system

increased lung adenocarcinoma incidence ( J:111629 )

• 16.8% of mice develop lung adenocarcenomas

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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