Dnai7Gt(VICTR21)709Lex
Gene trapped Allele Detail
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Symbol: |
Dnai7Gt(VICTR21)709Lex |
Name: |
dynein axonemal intermediate chain 7; gene trap 709, Lexicon Genetics |
MGI ID: |
MGI:3664581 |
Synonyms: |
Casc1ko |
Gene: |
Dnai7 Location: Chr6:145120560-145156731 bp, - strand Genetic Position: Chr6, 77.37 cM
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Alliance: |
Dnai7Gt(VICTR21)709Lex page
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Germline Transmission: |
Earliest citation of germline transmission:
J:111629
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S5/SvEvBrd
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Project Collection: |
Lexicon
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Allele Type: |
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Gene trapped (Null/knockout) |
Mutation: |
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Insertion of gene trap vector
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Mutation details: A VICTR21 retroviral promoter trap was inserted into intron 10, inactivating Casc1. The integration physically splits the Casc1 gene by producing two fusion transcripts. The splice donor in VICTR21 is preceded by stop codons in all three reading frames to prevent expression of fusion transcripts.
(J:111629)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Dnai7 Mutation: |
32 strains or lines available
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Original: |
J:111629 Liu P, et al., Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice. Nat Genet. 2006 Aug;38(8):888-95 |
All: |
1 reference(s) |
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