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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pias4tm1Hwu
targeted mutation 1, Hong Wu
MGI:3046514
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pias4tm1Hwu/Pias4tm1Hwu 129-Pias4tm1Hwu MGI:3046516
hm2
 		Pias4tm1Hwu/Pias4tm1Hwu involves: 129 * C57BL/6 MGI:3046515


Genotype
MGI:3046516
hm1
Allelic
Composition		 Pias4tm1Hwu/Pias4tm1Hwu
Genetic
Background		 129-Pias4tm1Hwu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pias4tm1Hwu mutation (0 available); any Pias4 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:91085 )
• Background Sensitivity: on a pure 129X1/SvJ background no obvious abnormalities are seen




Genotype
MGI:3046515
hm2
Allelic
Composition		 Pias4tm1Hwu/Pias4tm1Hwu
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pias4tm1Hwu mutation (0 available); any Pias4 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality ( J:91085 )
• Background Sensitivity: fewer than expected homozygous pups are found on a mixed 129X1/SvJ and C57BL/6 background but not on a pure 129X1/SvJ background
• surviving homozygotes are otherwise normal and fertile




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory