Phenotypes associated with this allele
Allelic Composition |
Tfectm1Est/Tfectm1Est
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Genetic Background |
either: (involves: 129/Sv * 129S1/Sv) or (involves: 129S1/Sv * C57BL/6J) |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tfectm1Est mutation
(0 available);
any
Tfec mutation
(25 available)
|
|
|
normal phenotype
|
• mice were indistinguishable from their wild-type littermates; exhibiting normal eyes, pigment, mast cells, osteoclasts and placentas
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MitfMi-wh mutation
(8 available);
any
Mitf mutation
(72 available)
Tfectm1Est mutation
(0 available);
any
Tfec mutation
(25 available)
|
|
|
pigmentation
skeleton
N |
• osteopetrosis is not observed amd bone development appears normal
|
vision/eye
integument
pigmentation
skeleton
|
• mice develop osteopetrosis similar to that observed in double MitfMi-wh and Tcfe3tm1Est mutants
|
vision/eye
integument
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MitfMi mutation
(3 available);
any
Mitf mutation
(72 available)
Tfectm1Est mutation
(0 available);
any
Tfec mutation
(25 available)
|
|
|
pigmentation
skeleton
vision/eye
integument
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tfe3tm1Est mutation
(1 available);
any
Tfe3 mutation
(21 available)
Tfectm1Est mutation
(0 available);
any
Tfec mutation
(25 available)
|
|
|
normal phenotype
|
• mice were indistinguishable from their wild-type littermates; exhibiting normal eyes, pigment, mast cells, osteoclasts and placentas
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tfebtm1Est mutation
(0 available);
any
Tfeb mutation
(45 available)
Tfectm1Est mutation
(0 available);
any
Tfec mutation
(25 available)
|
|
|
normal phenotype
|
• mice exhibit normal eyes, pigment, mast cells, and osteoclasts
|