All Phenotypes Tg(MMTV-cre)BElee MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(MMTV-cre)BElee
transgene insertion B, Eva YHP Lee
MGI:3043448

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Trp53^tm1Elee/Trp53^tm1Elee Tg(MMTV-cre)BElee/0	involves: 129S4/SvJae * C57BL/6	MGI:3044055

Allelic Composition	Trp53^tm1Elee/Trp53^tm1Elee Tg(MMTV-cre)BElee/0
Genetic Background	involves: 129S4/SvJae * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(MMTV-cre)BElee mutation (0 available)
Trp53^tm1Elee mutation (0 available); any Trp53 mutation (232 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased tumor incidence ( J:90247 )

• mean tumor latency about 11 months but with lower penetrance due to other tumor types

increased mammary adenocarcinoma incidence ( J:90247 )

• all mammalian tumors were adenocarcinomas, myoepithelial adenocarcinomas, adenosquamous carcinomas, or spindle cell tumors

• mostly poorly differentiated and invasive

integument

increased mammary adenocarcinoma incidence ( J:90247 )

• all mammalian tumors were adenocarcinomas, myoepithelial adenocarcinomas, adenosquamous carcinomas, or spindle cell tumors

• mostly poorly differentiated and invasive

endocrine/exocrine glands

increased mammary adenocarcinoma incidence ( J:90247 )

• all mammalian tumors were adenocarcinomas, myoepithelial adenocarcinomas, adenosquamous carcinomas, or spindle cell tumors

• mostly poorly differentiated and invasive

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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