All Phenotypes Scn8a<tm1Mm> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Scn8a^tm1Mm
targeted mutation 1, Miriam Meisler
MGI:3043395

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Scn8a^tm1Mm/Scn8a^tm1Mm Tg(Zp3-cre)3Mrt/?	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	MGI:3050792

Allelic Composition	Scn8a^tm1Mm/Scn8a^tm1Mm Tg(Zp3-cre)3Mrt/?
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn8a^tm1Mm mutation (0 available); any Scn8a mutation (99 available)
Tg(Zp3-cre)3Mrt mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:91696 )

• died between 3 and 4 weeks of age

behavior/neurological

ataxia ( J:91696 )

• by 14 days of age

hindlimb paralysis ( J:91696 )

• follows development of ataxia

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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