All Phenotypes Scn8a<tm1Mm> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Scn8a^tm1Mm
targeted mutation 1, Miriam Meisler
MGI:3043395

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Scn8a^tm1Mm/Scn8a^tm1Mm Tg(Zp3-cre)3Mrt/?	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	MGI:3050792

Allelic Composition	Scn8a^tm1Mm/Scn8a^tm1Mm Tg(Zp3-cre)3Mrt/?
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn8a^tm1Mm mutation (1 available); any Scn8a mutation (100 available)
Tg(Zp3-cre)3Mrt mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:91696 )

• died between 3 and 4 weeks of age

behavior/neurological

ataxia ( J:91696 )

• by 14 days of age

hindlimb paralysis ( J:91696 )

• follows development of ataxia

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24