All Phenotypes Vsx1<tm2Bhr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Vsx1^tm2Bhr
targeted mutation 2, Richard R Behringer
MGI:3040318

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Vsx1^tm1Bhr/Vsx1^tm2Bhr	involves: 129S4/SvJae * C57BL/6	MGI:3041677

Allelic Composition	Vsx1^tm1Bhr/Vsx1^tm2Bhr
Genetic Background	involves: 129S4/SvJae * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vsx1^tm1Bhr mutation (0 available); any Vsx1 mutation (10 available)
Vsx1^tm2Bhr mutation (0 available); any Vsx1 mutation (10 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

vision/eye phenotype ( J:89292 )

N	• at 3 weeks of age, heterozygotes exhibit normal-sized eyes and have retinas with a typical layered structure of three nuclear layers, similar to those seen in wild-type mice

abnormal retina cone bipolar cell morphology ( J:89292 )

• heterozygotes display impaired differentiation of cone bipolar cells, as shown by marker analyses of adult retinas by immunohistochemistry

• in contrast, retinal rod bipolar cell differentiation remains unaffected

nervous system

abnormal retina cone bipolar cell morphology ( J:89292 )

• heterozygotes display impaired differentiation of cone bipolar cells, as shown by marker analyses of adult retinas by immunohistochemistry

• in contrast, retinal rod bipolar cell differentiation remains unaffected

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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