Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crlf2tm1Jni mutation
(0 available);
any
Crlf2 mutation
(21 available)
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immune system
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• LPS-stimulated dendritic cells transferred into wild-type mice exhibit neutrophil-dominant airway inflammation compared with an eosinophil-dominant infiltration induced by wild-type dendritic cells
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respiratory system
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• LPS-stimulated dendritic cells transferred into wild-type mice exhibit neutrophil-dominant airway inflammation compared with an eosinophil-dominant infiltration induced by wild-type dendritic cells
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crlf2tm1Jni mutation
(0 available);
any
Crlf2 mutation
(21 available)
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hematopoietic system
N |
• normal hematological parameters and hematopoietic cell development
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immune system
N |
• normal thymus, spleen, and lymph node morphology
• normal B and T cell development
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crlf2tm1Jni mutation
(0 available);
any
Crlf2 mutation
(21 available)
Jak3tm1Jni mutation
(0 available);
any
Jak3 mutation
(84 available)
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hematopoietic system
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• loss of the residual splenic B220+ lymphoctyte population that persists in Jak3tm1Jni homozygotes
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immune system
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• loss of the residual splenic B220+ lymphoctyte population that persists in Jak3tm1Jni homozygotes
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