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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bace1tm1Cdi
targeted mutation 1, Colin Dingwall
MGI:2684825
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Bace1tm1Cdi/Bace1tm1Cdi involves: 129P2/OlaHsd * C57BL/6J MGI:2684842


Genotype
MGI:2684842
hm1
Allelic
Composition		 Bace1tm1Cdi/Bace1tm1Cdi
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bace1tm1Cdi mutation (0 available); any Bace1 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
decreased exploration in new environment ( J:86936 )
• spent less time in the center in an open field test and traveled shorter distances
• examined fewer holes in a holeboard exploration test
abnormal anxiety-related response ( J:86936 )
• produced more feces during open field tests
improved righting response ( J:86936 )
• improved righting ability in wire maneuver test

muscle
abnormal muscle physiology ( J:86936 )
• slightly firmer limb tone than in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory