Phenotypes associated with this allele

• Allele Symbol: Slc22a2^tm1Ahs
• Allele Name: targeted mutation 1, Alfred H Schinkel
• Allele ID: MGI:2680270
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc22a2^tm1Ahs/Slc22a2^tm1Ahs	involves: 129P2/OlaHsd * FVB	MGI:2680274

Genotype
MGI:2680274

hm1

• Allelic Composition: Slc22a2^tm1Ahs/Slc22a2^tm1Ahs
• Genetic Background: involves: 129P2/OlaHsd * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:86270 )

• homozygotes are viable, fertile, and show normal plasma clinical chemistry as well as normal liver, kidney, and intestine histology

• at 20 min after i.v. administration of [¹⁴C]-tetraethylammonium (TEA) at 0.2 mg/kg, no significant differences are observed in the distribution and excretion of this prototypic organic cation relative to wild-type controls, except for the brain, where levels are reduced with borderline significance