Analysis Tools
mortality/aging
|
• homozygous embryos die at or before the morula stage
|
|
Allele Symbol Allele Name Allele ID |
Tkttm1Jpi targeted mutation 1, Joram Piatigorsky MGI:2671068 |
| Summary |
2 genotypes |
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• homozygous embryos die at or before the morula stage
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• average weight of the fat tissues in heterozygous mice was 22% of control weight
|
 |
• infrequent mating noted in some females
|
|
• average weight of the heart in heterozygous mice was 85% of control weight
|
 |
• average weight of the testes in heterozygous mice was 67% of control weight
|
|
• mice were 60-64% smaller than wild-type littermates at 1 year of age
|
|
• average weight of the liver in heterozygous mice was 64% of control weight
|
|
• average weight of the kidney in heterozygous mice was 82% of control weight
|
|
|
• average weight of the testes in heterozygous mice was 67% of control weight
|
|
• as judged by number of pups delivered to heterozygous females
|
|
• small eye; average weight of the eyes in heterozygous mice was 93% of control weight
• however, corneas exhibited normal clarity and normal histology
|
|
• average weight of the brain in heterozygous mice was 92% of control weight
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/23/2024 MGI 6.23 |
|
|
|
||