Phenotypes associated with this allele

• Allele Symbol: Hbnr2^SWR
• Allele Name: SWR
• Allele ID: MGI:2660606
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hbnr2^SWR/Hbnr2^SWR	involves: CBA * SWR	MGI:2687258
ht2	Hbnr2^CBA/Hbnr2^SWR	involves: CBA * SWR	MGI:2687259
ot3	Hbnr2^SWR/?	involves: CBA * SWR	MGI:2674228

Genotype
MGI:2687258

hm1

• Allelic Composition: Hbnr2^SWR/Hbnr2^SWR
• Genetic Background: involves: CBA * SWR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased IgE level ( J:85787 )

granulomatous inflammation ( J:85787 )

• increased granuloma score

decreased susceptibility to parasitic infection ( J:110034 )

• decreased fecal egg count

• decreased total worm count

• increased intestinal mucosa granuloma score

• decreased IgG1 on adult worm

• decreased IgE on L4 larva

• increased IgG1 on L4 larva

• increased mucosal mast cell protease 1

hematopoietic system

decreased IgE level ( J:85787 )

Genotype
MGI:2687259

ht2

• Allelic Composition: Hbnr2^CBA/Hbnr2^SWR
• Genetic Background: involves: CBA * SWR

immune system

granulomatous inflammation ( J:85787 )

• increased granuloma score

Genotype
MGI:2674228

ot3

• Allelic Composition: Hbnr2^SWR/?
• Genetic Background: involves: CBA * SWR

immune system

decreased susceptibility to parasitic infection ( J:82261 )

• resistance to infection by Heligmosomoides polygyrus