Phenotypes associated with this allele

• Allele Symbol: Fmn1^ld-3J
• Allele Name: limb deformity 3 Jackson
• Allele ID: MGI:2654744
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fmn1^ld-3J/Fmn1^ld-3J	NOD.Cg Prkdc^scid/J-Fmn1^ld-3J/GrsrJ	MGI:2655420

Genotype
MGI:2655420

hm1

• Allelic Composition: Fmn1^ld-3J/Fmn1^ld-3J
• Genetic Background: NOD.Cg Prkdc^scid/J-Fmn1^ld-3J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

perinatal lethality, incomplete penetrance ( J:82800 )

• frequency of stillborn or neonatal death suggest significant perinatal lethality

skeleton

abnormal carpal bone morphology ( J:82800 )

• carpal and metacarpal bones disorganized and some digits missing on all four feet

abnormal ulna morphology ( J:82800 )

abnormal fibula morphology ( J:82800 )

• radius and fibula fuse into one flat bone, but long bone abnormalities are only found distal to the elbow or knee and humerus, femur, pelvis, pectoral girdle, and spinal vertebrae are normal

abnormal metacarpal bone morphology ( J:82800 )

limbs/digits/tail

abnormal carpal bone morphology ( J:82800 )

• carpal and metacarpal bones disorganized and some digits missing on all four feet

oligodactyly ( J:82800 )

syndactyly ( J:82800 )

• 3 digits on the front feet and disorganized metacarpals with syndactyly and oligodactyly affecting all 4 feet

abnormal ulna morphology ( J:82800 )

abnormal fibula morphology ( J:82800 )

• radius and fibula fuse into one flat bone, but long bone abnormalities are only found distal to the elbow or knee and humerus, femur, pelvis, pectoral girdle, and spinal vertebrae are normal

abnormal metacarpal bone morphology ( J:82800 )

short limbs ( J:82800 )

renal/urinary system

single kidney ( J:82800 )

• one homozygous male had only one kidney

reproductive system

male infertility ( J:82800 )

♂ • males have not been found to breed