About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pou2f3tm1Rsd
targeted mutation 1, Michael G Rosenfeld
MGI:2450109
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pou2f3tm1Rsd/Pou2f3tm1Rsd involves: 129/Sv * 129S4/SvJae * C57BL/6J MGI:2655767
cx2
 		Pou2f3tm1Rsd/Pou2f3tm1Rsd
Pou3f1tm1Rsd/Pou3f1tm1Rsd 		involves: 129/Sv * 129S4/SvJae * C57BL/6J MGI:2665472


Genotype
MGI:2655767
hm1
Allelic
Composition		 Pou2f3tm1Rsd/Pou2f3tm1Rsd
Genetic
Background		 involves: 129/Sv * 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pou2f3tm1Rsd mutation (0 available); any Pou2f3 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
integument phenotype ( J:42016 )
N
• skin and coat appeared grossly normal
abnormal keratinocyte differentiation ( J:42016 )
• abnormal epidermal layer: defective keratinocyte differentiation

cellular
abnormal keratinocyte differentiation ( J:42016 )
• abnormal epidermal layer: defective keratinocyte differentiation




Genotype
MGI:2665472
cx2
Allelic
Composition		 Pou2f3tm1Rsd/Pou2f3tm1Rsd
Pou3f1tm1Rsd/Pou3f1tm1Rsd
Genetic
Background		 involves: 129/Sv * 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pou2f3tm1Rsd mutation (0 available); any Pou2f3 mutation (36 available)
Pou3f1tm1Rsd mutation (0 available); any Pou3f1 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, incomplete penetrance ( J:42016 )
• most mice die soon after birth

integument
integument phenotype ( J:42016 )
N
• no overt skin abnormalities in neonates




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory