Phenotypes associated with this allele

• Allele Symbol: Fbxl3^Ovtm
• Allele Name: overtime
• Allele ID: MGI:2449078
• Summary: 7 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fbxl3^Ovtm/Fbxl3^Ovtm	BTBR T^+ Itpr3^tf/Itpr3^tf-Fbxl3^Ovtm/Nwu	MGI:2661870
hm2	Fbxl3^Ovtm/Fbxl3^Ovtm	involves: BTBR * C57BL/6J	MGI:5484574
hm3	Fbxl3^Ovtm/Fbxl3^Ovtm	involves: BTBR/J * C3H/HeJ * C57BL/6J	MGI:3717257
ht4	Fbxl3^Ovtm/Fbxl3^+	BTBR T^+ Itpr3^tf/Itpr3^tf-Fbxl3^Ovtm/Nwu	MGI:2661872
ht5	Fbxl3^Gt(FHCRC-GT-S13-12G1)Sor/Fbxl3^Ovtm	involves: BTBR/J * C3H/HeJ * C57BL/6J	MGI:3717258
cx6	Fbxl3^Ovtm/Fbxl3^Ovtm Nr1d1^tm1Schb/Nr1d1^tm1Schb	involves: 129S2/SvPas * BTBR	MGI:5494574
cx7	Fbxl21^Psttm/Fbxl21^Psttm Fbxl3^Ovtm/Fbxl3^Ovtm	involves: BTBR * C57BL/6J	MGI:5484573

Genotype
MGI:2661870

hm1

• Allelic Composition: Fbxl3^Ovtm/Fbxl3^Ovtm
• Genetic Background: BTBR T⁺ Itpr3^tf/Itpr3^tf-Fbxl3^Ovtm/Nwu

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

prolonged circadian behavior period ( J:83419 )

• homozygous mutant mice display a longer free running period than that of wild-type mice (25.88 hrs vs.23.27 hrs 0.13 sd)

Genotype
MGI:5484574

hm2

• Allelic Composition: Fbxl3^Ovtm/Fbxl3^Ovtm
• Genetic Background: involves: BTBR * C57BL/6J

behavior/neurological

prolonged circadian behavior period ( J:194037 )

• period length is 26 hr

Genotype
MGI:3717257

hm3

• Allelic Composition: Fbxl3^Ovtm/Fbxl3^Ovtm
• Genetic Background: involves: BTBR/J * C3H/HeJ * C57BL/6J

behavior/neurological

prolonged circadian behavior period ( J:122872 )

• circadian period is extended to 26.2 hours compared to 25.8 in wild-type mice

Genotype
MGI:2661872

ht4

• Allelic Composition: Fbxl3^Ovtm/Fbxl3⁺
• Genetic Background: BTBR T⁺ Itpr3^tf/Itpr3^tf-Fbxl3^Ovtm/Nwu

behavior/neurological

prolonged circadian behavior period ( J:83419 )

• heterozygous mutant mice display a longer free running period than that of wild-type mice (23.97 hrs vs.23.27 hrs 0.13 sd)

Genotype
MGI:3717258

ht5

• Allelic Composition: Fbxl3^{Gt(FHCRC-GT-S13-12G1)Sor}/Fbxl3^Ovtm
• Genetic Background: involves: BTBR/J * C3H/HeJ * C57BL/6J

behavior/neurological

prolonged circadian behavior period ( J:122872 )

• circadian period is extended similar to in Fbxl3^Ovtm homozygotes

Genotype
MGI:5494574

cx6

• Allelic Composition: Fbxl3^Ovtm/Fbxl3^Ovtm; Nr1d1^tm1Schb/Nr1d1^tm1Schb
• Genetic Background: involves: 129S2/SvPas * BTBR

behavior/neurological

behavior/neurological phenotype ( J:194250 )

N • 23.7 hour circadian rhythm is relatively normal

Genotype
MGI:5484573

cx7

• Allelic Composition: Fbxl21^Psttm/Fbxl21^Psttm; Fbxl3^Ovtm/Fbxl3^Ovtm
• Genetic Background: involves: BTBR * C57BL/6J

behavior/neurological

behavior/neurological phenotype ( J:194037 )

N • circadian period is 23.16 hr similar to that in wild-type controls and significantly shorter than the predicted 24.4 hr of an additive effect