Fbxl3^{Gt(FHCRC-GT-S13-12G1)Sor}
Gene trapped Allele Detail

Summary

• Symbol: Fbxl3^{Gt(FHCRC-GT-S13-12G1)Sor}
• Name: F-box and leucine-rich repeat protein 3; gene trap FHCRC-GT-S13-12G1, Philippe Soriano
• MGI ID: MGI:3716750
• Gene: Fbxl3 Location: Chr14:103317675-103337002 bp, - strand Genetic Position: Chr14, 51.73 cM, cytoband E2.2
• Alliance: Fbxl3^{Gt(FHCRC-GT-S13-12G1)Sor} page

Mutation origin

• Mutant Cell Line: S13-12G1
• Germline Transmission: Earliest citation of germline transmission: J:122872
• Parent Cell Line: AK7.1 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: ROSAFARY
• The ROSAFARY gene trap vector was inserted to disrupt the locus. (J:122872)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  FHCRC-GT-S13-12G1	CL458948 ; (MGI Seq Detail)	3' RACE	Chr14:103320801-103332976 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  25 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fbxl3 Mutation: 41 strains or lines available

References

• Original: J:122872 Siepka SM, et al., Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression. Cell. 2007 Jun 1;129(5):1011-23
• All: 1 reference(s)