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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tsg101tm1.1Kuw
targeted mutation 1.1, Kay-Uwe Wagner
MGI:2447444
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tsg101tm1.1Kuw/Tsg101tm1.1Kuw Not Specified MGI:2447779
ht2
 		Tsg101tm1.1Kuw/Tsg101+ Not Specified MGI:2447780


Genotype
MGI:2447779
hm1
Allelic
Composition		 Tsg101tm1.1Kuw/Tsg101tm1.1Kuw
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tsg101tm1.1Kuw mutation (0 available); any Tsg101 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:80891 )
• blastocyts were indistinguishable from wild-type littermates at E3.5, but homozygous embryos were undetectable after the implantation stage




Genotype
MGI:2447780
ht2
Allelic
Composition		 Tsg101tm1.1Kuw/Tsg101+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tsg101tm1.1Kuw mutation (0 available); any Tsg101 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
neoplasm ( J:80891 )
N
• mice more than 21 months of age did not exhibit any palpable tumors




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory