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Targeted Allele Detail
Symbol: Tsg101tm1.1Kuw
Name: tumor susceptibility gene 101; targeted mutation 1.1, Kay-Uwe Wagner
MGI ID: MGI:2447444
Synonyms: Tsg101-
Gene: Tsg101  Location: Chr7:46538697-46569717 bp, - strand  Genetic Position: Chr7, 30.62 cM, cytoband B5
Alliance: Tsg101tm1.1Kuw page
Germline Transmission:  Earliest citation of germline transmission: J:80891
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThe loxP flanked genomic fragment encompassing the promoter region and exon 1 was excised from tsg101tm1Kuw via cre mediated recombination in the germline. (J:80891)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tsg101 Mutation:  22 strains or lines available
Original:  J:80891 Wagner KU, et al., Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues. Mol Cell Biol. 2003 Jan;23(1):150-62
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory