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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nqo2tm1Akj
targeted mutation 1, Anil K Jaiswal
MGI:2447336
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nqo2tm1Akj/Nqo2tm1Akj Not Specified MGI:3522037


Genotype
MGI:3522037
hm1
Allelic
Composition		 Nqo2tm1Akj/Nqo2tm1Akj
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nqo2tm1Akj mutation (0 available); any Nqo2 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased skin tumor incidence ( J:92400 )
• in two stage tests increased sensitivity to chemically induced tumors

hematopoietic system
abnormal lymphopoiesis ( J:80549 )
• reduced numbers of circulating lymphocytes

homeostasis/metabolism
abnormal enzyme/coenzyme activity ( J:80549 )
• less susceptible to vitamin K3 toxicity (menadione)

immune system
abnormal lymphopoiesis ( J:80549 )
• reduced numbers of circulating lymphocytes

integument
increased skin tumor incidence ( J:92400 )
• in two stage tests increased sensitivity to chemically induced tumors




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory