Phenotypes associated with this allele

• Allele Symbol: Psca⁺
• Allele Name: wild type
• Allele ID: MGI:2440743
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Psca^tm1Witt/Psca^+ Tg(TRAMP)8247Ng/0	involves: 129/Sv * C57BL/6	MGI:3795484

Genotype
MGI:3795484

cx1

• Allelic Composition: Psca^tm1Witt/Psca⁺; Tg(TRAMP)8247Ng/0
• Genetic Background: involves: 129/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased prostate gland tumor incidence ( J:133908 )

♂ • mice are moribund with prostrate tumors on average at 34.4 weeks of age

♂ • intraepithelial neoplasia and adenocarcinomas at different stages of differentiation are observed in the prostrate

♂ • there is a increased incidence of metastasis compared to mice that carry just the transgene

increased prostate gland adenocarcinoma incidence ( J:133908 )

♂

increased prostate intraepithelial neoplasia incidence ( J:133908 )

♂

reproductive system

increased prostate gland tumor incidence ( J:133908 )

♂ • mice are moribund with prostrate tumors on average at 34.4 weeks of age

♂ • intraepithelial neoplasia and adenocarcinomas at different stages of differentiation are observed in the prostrate

♂ • there is a increased incidence of metastasis compared to mice that carry just the transgene

increased prostate gland adenocarcinoma incidence ( J:133908 )

♂

increased prostate intraepithelial neoplasia incidence ( J:133908 )

♂

endocrine/exocrine glands

increased prostate gland tumor incidence ( J:133908 )

♂ • mice are moribund with prostrate tumors on average at 34.4 weeks of age

♂ • intraepithelial neoplasia and adenocarcinomas at different stages of differentiation are observed in the prostrate

♂ • there is a increased incidence of metastasis compared to mice that carry just the transgene

increased prostate gland adenocarcinoma incidence ( J:133908 )

♂

increased prostate intraepithelial neoplasia incidence ( J:133908 )

♂