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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ube2b+
wild type
MGI:2440208
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Ube2btm1a(EUCOMM)Wtsi/Ube2b+ C57BL/6N-Ube2btm1a(EUCOMM)Wtsi/Ics MGI:5782219
ht2
 		Ube2btm1b(EUCOMM)Wtsi/Ube2b+ C57BL/6N-Ube2btm1b(EUCOMM)Wtsi/Ics MGI:5757838
cx3
 		Ube2atm1Agr/Y
Ube2btm1Jhjh/Ube2b+ 		involves: 129P2/OlaHsd * FVB/N MGI:3051838
cx4
 		Ube2atm1Agr/Ube2atm1Agr
Ube2btm1Jhjh/Ube2b+ 		involves: 129P2/OlaHsd * FVB/N MGI:3051849


Genotype
MGI:5782219
ht1
Allelic
Composition		 Ube2btm1a(EUCOMM)Wtsi/Ube2b+
Genetic
Background		 C57BL/6N-Ube2btm1a(EUCOMM)Wtsi/Ics
Cell Lines EPD0038_4_D01
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ube2btm1a(EUCOMM)Wtsi mutation (2 available); any Ube2b mutation (21 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological

homeostasis/metabolism




Genotype
MGI:5757838
ht2
Allelic
Composition		 Ube2btm1b(EUCOMM)Wtsi/Ube2b+
Genetic
Background		 C57BL/6N-Ube2btm1b(EUCOMM)Wtsi/Ics
Cell Lines EPD0038_4_D01
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ube2btm1b(EUCOMM)Wtsi mutation (1 available); any Ube2b mutation (21 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
limb grasping ( J:211773 )
IMPC - HAR
abnormal gait ( J:211773 )
IMPC - HAR

cardiovascular system
enlarged heart ( J:211773 )
IMPC - HAR

growth/size/body
enlarged heart ( J:211773 )
IMPC - HAR

hematopoietic system

immune system

integument




Genotype
MGI:3051838
cx3
Allelic
Composition		 Ube2atm1Agr/Y
Ube2btm1Jhjh/Ube2b+
Genetic
Background		 involves: 129P2/OlaHsd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ube2atm1Agr mutation (0 available); any Ube2a mutation (6 available)
Ube2btm1Jhjh mutation (0 available); any Ube2b mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:91848 )
• fewer than expected male mutants are found at birth

growth/size/body
decreased birth weight ( J:91848 )
• body weight is markedly reduced at birth
decreased body weight ( J:91848 )
• a body weight reduction of about 37% compared to wild-type littermates is seen at 10 days of age

reproductive system
reproductive system phenotype ( J:91848 )
N
• males are fertile




Genotype
MGI:3051849
cx4
Allelic
Composition		 Ube2atm1Agr/Ube2atm1Agr
Ube2btm1Jhjh/Ube2b+
Genetic
Background		 involves: 129P2/OlaHsd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ube2atm1Agr mutation (0 available); any Ube2a mutation (6 available)
Ube2btm1Jhjh mutation (0 available); any Ube2b mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:91848 )
• fewer than expected female mutants are found at birth

growth/size/body
decreased body weight ( J:91848 )
• body weight reduction of about 31% compared to wild-type littermates is seen at 10 days of age




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory