Phenotypes associated with this allele

• Allele Symbol: Slc5a7⁺
• Allele Name: wild type
• Allele ID: MGI:2439670
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Slc5a7^tm1a(KOMP)Wtsi/Slc5a7^+	C57BL/6N-Slc5a7^tm1a(KOMP)Wtsi/Wtsi	MGI:5706096
ht2	Slc5a7^tm1Rbl/Slc5a7^+	involves: 129S6/SvEvTac * C57BL/6	MGI:3045590

Genotype
MGI:5706096

ht1

• Allelic Composition: Slc5a7^{tm1a(KOMP)Wtsi}/Slc5a7⁺
• Genetic Background: C57BL/6N-Slc5a7^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0742_5_H10

Data Sources

IMPC Data for Slc5a7

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - WTSI

behavior/neurological

increased grip strength ( J:211773 )

IMPC - WTSI

homeostasis/metabolism

decreased circulating fructosamine level ( J:211773 )

♂

IMPC - WTSI

integument

abnormal hair growth ( J:211773 )

♂

IMPC - WTSI

Genotype
MGI:3045590

ht2

• Allelic Composition: Slc5a7^tm1Rbl/Slc5a7⁺
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

mortality/aging

increased susceptibility to xenobiotic induced morbidity/mortality ( J:90846 )

• heterozygotes are more sensitive to hemicholinium (inhibits choline uptake) toxicity, with 60% of heterozygotes dying at a concentration that is not lethal to wild-type mice

homeostasis/metabolism

increased susceptibility to xenobiotic induced morbidity/mortality ( J:90846 )

• heterozygotes are more sensitive to hemicholinium (inhibits choline uptake) toxicity, with 60% of heterozygotes dying at a concentration that is not lethal to wild-type mice