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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Syt10+
wild type
MGI:2439209
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Bmal1tm1Weit/Bmal1tm1Weit
Syt10tm1.1(icre)Geno/Syt10+ 		involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 MGI:5297479
cn2
 		Bmal1tm1Bra/Bmal1tm1Weit
Syt10tm1.1(icre)Geno/Syt10+ 		involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 MGI:5297480


Genotype
MGI:5297479
cn1
Allelic
Composition		 Bmal1tm1Weit/Bmal1tm1Weit
Syt10tm1.1(icre)Geno/Syt10+
Genetic
Background		 involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmal1tm1Weit mutation (1 available); any Bmal1 mutation (137 available)
Syt10tm1.1(icre)Geno mutation (0 available); any Syt10 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
shortened circadian behavior period ( J:175596 )
• mice show a shortened period under constant dark conditions (DD) compared to controls; animals are still rhythmic under constant light and dark conditions, but rhythmicity under DD is less stable compared to controls (mutants show increased onset variability relative to controls)




Genotype
MGI:5297480
cn2
Allelic
Composition		 Bmal1tm1Bra/Bmal1tm1Weit
Syt10tm1.1(icre)Geno/Syt10+
Genetic
Background		 involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmal1tm1Bra mutation (1 available); any Bmal1 mutation (137 available)
Bmal1tm1Weit mutation (1 available); any Bmal1 mutation (137 available)
Syt10tm1.1(icre)Geno mutation (0 available); any Syt10 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal circadian behavior ( J:175596 )
• animals display impaired activity rhythms but are not totally arrhythmic
shortened circadian behavior period ( J:175596 )
• animals have a shorter period in constant light conditions (DD); mutants have higher onset errors than wild-type controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory