All Phenotypes Apoc3<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Apoc3⁺
wild type
MGI:2439062

Summary

2 genotypes

Allelic Composition	Apoc3^tm1Unc/Apoc3⁺
Genetic Background	involves: 129

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoc3^tm1Unc mutation (2 available); any Apoc3 mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

• total plasma cholesterol levels are slightly reduced in male but not female mice

• VLDL+LDL cholesterol levels are reduced by half in male but not female mice

• VLDL+LDL cholesterol levels are reduced by half in male but not female mice

• plasma triglycerides are reduced by 30% in both female and male mice

Allelic Composition	Apoc3^tm1Unc/Apoc3⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoc3^tm1Unc mutation (2 available); any Apoc3 mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

• total plasma cholesterol levels are reduced by 15% in female but not male mice

• HDL cholesterol levels are reduced by 10% in female but not male mice

• plasma triglycerides are reduced by 15% in both female and male mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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