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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lats2+
wild type
MGI:2438790
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Lats2tm1Dgen/Lats2+ involves: 129P2/OlaHsd * C57BL/6 MGI:3606568
ht2
 		Lats2tm1Noj/Lats2+ involves: 129S2/SvPas * C57BL/6 MGI:3720101


Genotype
MGI:3606568
ht1
Allelic
Composition		 Lats2tm1Dgen/Lats2+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lats2tm1Dgen mutation (1 available); any Lats2 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal startle reflex ( J:101679 )
• prepulse inhibition is significantly decreased




Genotype
MGI:3720101
ht2
Allelic
Composition		 Lats2tm1Noj/Lats2+
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lats2tm1Noj mutation (1 available); any Lats2 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:123480 )
• males embryos experience more embryonic lethality than females




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/06/2026
MGI 6.29 		The Jackson Laboratory