Phenotypes associated with this allele

• Allele Symbol: Slc7a8⁺
• Allele Name: wild type
• Allele ID: MGI:2438762
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Slc7a8^tm2b(EUCOMM)Hmgu/Slc7a8^+	C57BL/6N-Slc7a8^tm2b(EUCOMM)Hmgu/Bay	MGI:6263514
ht2	Slc7a8^tm1Geno/Slc7a8^+	involves: 129 * C57BL/6J	MGI:6323256

Genotype
MGI:6263514

ht1

• Allelic Composition: Slc7a8^{tm2b(EUCOMM)Hmgu}/Slc7a8⁺
• Genetic Background: C57BL/6N-Slc7a8^{tm2b(EUCOMM)Hmgu}/Bay
• Cell Lines: HEPD0835_1_A06

Data Sources

IMPC Data for Slc7a8

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased circulating fructosamine level ( J:211773 )

♀

IMPC - HAR

limbs/digits/tail

short tibia ( J:211773 )

♀

IMPC - HAR

skeleton

short tibia ( J:211773 )

♀

IMPC - HAR

Genotype
MGI:6323256

ht2

• Allelic Composition: Slc7a8^tm1Geno/Slc7a8⁺
• Genetic Background: involves: 129 * C57BL/6J

hearing/vestibular/ear

abnormal spiral ligament fibrocyte morphology ( J:256844 )

• number of fibrocytes in the spiral ligament is decreased by 1/3

impaired hearing ( J:256844 )

• mice show increased hearing loss penetrance with age starting from 7 months onward

skeleton

abnormal spiral ligament fibrocyte morphology ( J:256844 )

• number of fibrocytes in the spiral ligament is decreased by 1/3