Slc7a8^tm1Geno
Targeted Allele Detail

Summary

• Symbol: Slc7a8^tm1Geno
• Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 8; targeted mutation 1, Genoway
• MGI ID: MGI:5660917
• Gene: Slc7a8 Location: Chr14:54959672-55019343 bp, - strand Genetic Position: Chr14, 27.91 cM
• Alliance: Slc7a8^tm1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:216253
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Part of the promoter and exon 1 were replaced with a neo cassette via homologous recombination. (J:216253)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc7a8 Mutation: 34 strains or lines available

References

• Original: J:216253 Nunez B, et al., Cerebral cortex hyperthyroidism of newborn mct8-deficient mice transiently suppressed by lat2 inactivation. PLoS One. 2014;9(5):e96915
• All: 3 reference(s)