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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Il22+
wild type
MGI:2438747
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
\Il22tm1Flv/\Il22+ B6.Cg-Il22tm1Flv MGI:3761617
cn2
\Gt(ROSA)26Sortm1(EYFP)Cos/\Gt(ROSA)26Sor+
\Il22tm1.1(icre)Stck/\Il22+
involves: 129X1/SvJ * C57BL/6N MGI:5634193


Genotype
MGI:3761617
ht1
Allelic
Composition
\Il22tm1Flv/\Il22+
Genetic
Background
B6.Cg-Il22tm1Flv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il22tm1Flv mutation (0 available); any Il22 mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• following injection of concanavalin, mice develop more lesions than wild-type mice but fewer than homozygous mice

immune system
• following injection concanavalin, 25% (at 10 ug/g) and 100% (at 20 ug/g) of mice die whereas no wild-type mice exhibit any outward signs of morbidity




Genotype
MGI:5634193
cn2
Allelic
Composition
\Gt(ROSA)26Sortm1(EYFP)Cos/\Gt(ROSA)26Sor+
\Il22tm1.1(icre)Stck/\Il22+
Genetic
Background
involves: 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(EYFP)Cos mutation (23 available); any Gt(ROSA)26Sor mutation (1097 available)
Il22tm1.1(icre)Stck mutation (1 available); any Il22 mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mice infected with Citrobacter exhibit increased transient weight loss compared with wild-type mice and mice heterozygous for a knock-out allele
• however, mice exhibit normal clearance and kinetics of infection

growth/size/body
• mice infected with Citrobacter exhibit increased transient weight loss compared with wild-type mice and mice heterozygous for a knock-out allele
• however, mice exhibit normal clearance and kinetics of infection





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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory