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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sec23b+
wild type
MGI:2438436
Summary 2 genotypes


Genotype
MGI:5818261
cx1
Allelic
Composition		 Sec23aGt(RRE297)Byg/Sec23a+
Sec23bGt(AD0407)Wtsi/Sec23b+
Genetic
Background		 B6J.129P2-Sec23bGt(AD0407)Wtsi Sec23aGt(RRE297)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sec23aGt(RRE297)Byg mutation (0 available); any Sec23a mutation (47 available)
Sec23bGt(AD0407)Wtsi mutation (0 available); any Sec23b mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:237614 )
• mice are viable and fertile with no detectable phenotype




Genotype
MGI:5818262
cx2
Allelic
Composition		 Sec23aGt(RRE297)Byg/Sec23aGt(RRE297)Byg
Sec23bGt(AD0407)Wtsi/Sec23b+
Genetic
Background		 B6J.129P2-Sec23bGt(AD0407)Wtsi Sec23aGt(RRE297)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sec23aGt(RRE297)Byg mutation (0 available); any Sec23a mutation (47 available)
Sec23bGt(AD0407)Wtsi mutation (0 available); any Sec23b mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality prior to organogenesis, incomplete penetrance ( J:237614 )
• only 5.6% (versus expected 12.5%) of embryos are observed at E9.5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory