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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Edar+
wild type
MGI:2438107
Summary 6 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Edartm1b(KOMP)Wtsi/Edar+ C57BL/6N-Edartm1b(KOMP)Wtsi/Ucd MGI:5797495
ht2
EdarDl-slk2H/Edar+ involves: 101/H * C3H/HeH MGI:5314356
ht3
Edartm1.1Bamo/Edar+ involves: 129S4/SvJae * FVB MGI:5484583
ht4
Edardl/Edar+ involves: A/H MGI:3693948
ht5
Edardl-J/Edar+ involves: C3HeB/FeJ MGI:5484584
ht6
EdarDl-slk/Edar+ Not Specified MGI:4868752


Genotype
MGI:5797495
ht1
Allelic
Composition
Edartm1b(KOMP)Wtsi/Edar+
Genetic
Background
C57BL/6N-Edartm1b(KOMP)Wtsi/Ucd
Cell Lines EPD0079_3_H09
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edartm1b(KOMP)Wtsi mutation (1 available); any Edar mutation (31 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system




Genotype
MGI:5314356
ht2
Allelic
Composition
EdarDl-slk2H/Edar+
Genetic
Background
involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
EdarDl-slk2H mutation (0 available); any Edar mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument

pigmentation




Genotype
MGI:5484583
ht3
Allelic
Composition
Edartm1.1Bamo/Edar+
Genetic
Background
involves: 129S4/SvJae * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edartm1.1Bamo mutation (0 available); any Edar mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• increase in the number of glands per footpad compared to wild-type mice but fewer than in homozygous mutants

integument
• increase in the number of glands per footpad compared to wild-type mice but fewer than in homozygous mutants

limbs/digits/tail
• increase in the number of glands per footpad compared to wild-type mice but fewer than in homozygous mutants




Genotype
MGI:3693948
ht4
Allelic
Composition
Edardl/Edar+
Genetic
Background
involves: A/H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edardl mutation (0 available); any Edar mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• heterozygotes may have mutant teeth, normal teeth or teeth combining mutant and normal characteristics
• additional molar tooth is a rare occurence

growth/size/body
• heterozygotes may have mutant teeth, normal teeth or teeth combining mutant and normal characteristics
• additional molar tooth is a rare occurence

skeleton
• heterozygotes may have mutant teeth, normal teeth or teeth combining mutant and normal characteristics
• additional molar tooth is a rare occurence




Genotype
MGI:5484584
ht5
Allelic
Composition
Edardl-J/Edar+
Genetic
Background
involves: C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edardl-J mutation (2 available); any Edar mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• subtle decrease in the number of glands per foot pad

integument
• subtle decrease in the number of glands per foot pad

limbs/digits/tail
• subtle decrease in the number of glands per foot pad




Genotype
MGI:4868752
ht6
Allelic
Composition
EdarDl-slk/Edar+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
EdarDl-slk mutation (0 available); any Edar mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• dental abnormalities are the same as known to occur in mice homozygous or hemizygous for EdaTa
• incisors are small or absent
• cusp B1 of m1 is absent
• cusp B3 of m1 and m2 are usually absent
• a ridge of variable height connects cusps B1 and L1, running transversely across the anterior end of the crown of m2
• the root of m1 is usually single, though sometimes two or three roots are present
• upper and lower third molars are small or absent
• upper and lower third molars are small or absent
• first and second molars are smaller than normal

craniofacial
• dental abnormalities are the same as known to occur in mice homozygous or hemizygous for EdaTa
• incisors are small or absent
• cusp B1 of m1 is absent
• cusp B3 of m1 and m2 are usually absent
• a ridge of variable height connects cusps B1 and L1, running transversely across the anterior end of the crown of m2
• the root of m1 is usually single, though sometimes two or three roots are present
• upper and lower third molars are small or absent
• upper and lower third molars are small or absent
• first and second molars are smaller than normal

integument
• mice look like homozygous or heterozygous Edardl mice
• coat is shiny and thin with bald patches behind the ears but the tail is sparsely haired rather than bald
• reduced number of vibrissae but more than found in the homozygous mouse

growth/size/body
• dental abnormalities are the same as known to occur in mice homozygous or hemizygous for EdaTa
• incisors are small or absent
• cusp B1 of m1 is absent
• cusp B3 of m1 and m2 are usually absent
• a ridge of variable height connects cusps B1 and L1, running transversely across the anterior end of the crown of m2
• the root of m1 is usually single, though sometimes two or three roots are present
• upper and lower third molars are small or absent
• upper and lower third molars are small or absent
• first and second molars are smaller than normal





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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory