Edar^dl
Spontaneous Allele Detail

Summary

• Symbol: Edar^dl
• Name: ectodysplasin-A receptor; downless
• MGI ID: MGI:1856016
• Synonyms: dl
• Gene: Edar Location: Chr10:58436611-58511476 bp, - strand Genetic Position: Chr10, 29.37 cM, cytoband B3
• Alliance: Edar^dl page

Mutation origin

• Strain of Origin: A/H

Mutation description

• Allele Type: Spontaneous
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Edar Mutation: 30 strains or lines available

Notes

Homozygotes closely resemble crinkled (cr/cr) mice and tabby homozygotes (Ta/Ta) and hemizygotes (Ta/Y).

Phenotypic Similarity to Human Syndrome: hypohidrotic/anhidrotic ectodermal dysplasia (OMIM 305100, 224900, and 129490). Similar phenotypes have also been described in mice for the Tabby allelic series at the Eda locus.

References

• Original: J:18293 Phillips RJS, New mutant. Mouse News Lett. 1960;23:29-30
• All: 16 reference(s)