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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bmpr1b+
wild type
MGI:2437675
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Bmpr1bTg(ACTB-FLP)4917Dym/Bmpr1b+ involves: C57BL/6 * SJL MGI:3702967
cn2
 		Bmpr1atm1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1b+
Tg(Six3-cre)69Frty/0 		involves: 129S/SvEv MGI:3574976
cx3
 		Bmpr1btm1Kml/Bmpr1b+
Gdf5bp-J/Gdf5+ 		involves: 129S/SvEv * A/J * C57BL/6J MGI:3789180


Genotype
MGI:3702967
ht1
Allelic
Composition		 Bmpr1bTg(ACTB-FLP)4917Dym/Bmpr1b+
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmpr1bTg(ACTB-FLP)4917Dym mutation (0 available); any Bmpr1b mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:59288 )
• heterozygous mice show no overt phenotype




Genotype
MGI:3574976
cn2
Allelic
Composition		 Bmpr1atm1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1b+
Tg(Six3-cre)69Frty/0
Genetic
Background		 involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmpr1atm1Bhr mutation (1 available); any Bmpr1a mutation (89 available)
Bmpr1atm2.1Bhr mutation (1 available); any Bmpr1a mutation (89 available)
Bmpr1btm1Kml mutation (0 available); any Bmpr1b mutation (41 available)
Tg(Six3-cre)69Frty mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal retina ganglion cell morphology ( J:96964 )
• many dorsal retinal ganglion cell axons form ectopic termination zones
• eye size and retinal layer morphology are normal

nervous system
abnormal retina ganglion cell morphology ( J:96964 )
• many dorsal retinal ganglion cell axons form ectopic termination zones
• eye size and retinal layer morphology are normal




Genotype
MGI:3789180
cx3
Allelic
Composition		 Bmpr1btm1Kml/Bmpr1b+
Gdf5bp-J/Gdf5+
Genetic
Background		 involves: 129S/SvEv * A/J * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmpr1btm1Kml mutation (0 available); any Bmpr1b mutation (41 available)
Gdf5bp-J mutation (2 available); any Gdf5 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal phalanx morphology ( J:59282 )
• 100% of mutants show delayed ossification of the middle phalanx

skeleton
abnormal phalanx morphology ( J:59282 )
• 100% of mutants show delayed ossification of the middle phalanx
delayed bone ossification ( J:59282 )
• 100% of mutants show delayed ossification of the middle phalanx




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory