All Phenotypes Egr3<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Egr3⁺
wild type
MGI:2436789

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gdnf^tm1Bbd/Gdnf^tm1.1Neas Egr3^tm1(cre)Mod/Egr3⁺	involves: 129S1/Sv * C57BL/6 * C57BL/6J * SJL	MGI:4456170

Allelic Composition	Gdnf^tm1Bbd/Gdnf^tm1.1Neas Egr3^tm1(cre)Mod/Egr3⁺
Genetic Background	involves: 129S1/Sv * C57BL/6 * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Egr3^tm1(cre)Mod mutation (0 available); any Egr3 mutation (20 available)
Gdnf^tm1.1Neas mutation (1 available); any Gdnf mutation (18 available)
Gdnf^tm1Bbd mutation (0 available); any Gdnf mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal cholinergic neuron morphology ( J:160727 )

• at P20, mice exhibit a decrease in small cholinergic motor neurons compared with wild-type mice

decreased motor neuron number ( J:160727 )

• at P20, mice exhibit a decrease in small cholinergic motor neurons compared with wild-type mice

• mice exhibit selective loss of gamma-motor neurons compared with wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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