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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cdk6+
wild type
MGI:2436637
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Cdk6tm1Phin/Cdk6+
Tg(Lck-Akt1*E40K)E-3Pnt/0 		involves: 129S4/SvJae MGI:3833619


Genotype
MGI:3833619
cx1
Allelic
Composition		 Cdk6tm1Phin/Cdk6+
Tg(Lck-Akt1*E40K)E-3Pnt/0
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdk6tm1Phin mutation (0 available); any Cdk6 mutation (38 available)
Tg(Lck-Akt1*E40K)E-3Pnt mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased tumor-free survival time ( J:144975 )
• most mice develop tumors by 22 weeks of age and die prematurely

neoplasm
increased T cell derived lymphoma incidence ( J:144975 )
• most mice develop tumors by 22 weeks of age and die prematurely

endocrine/exocrine glands
increased T cell derived lymphoma incidence ( J:144975 )
• most mice develop tumors by 22 weeks of age and die prematurely

immune system
increased T cell derived lymphoma incidence ( J:144975 )
• most mice develop tumors by 22 weeks of age and die prematurely

hematopoietic system
increased T cell derived lymphoma incidence ( J:144975 )
• most mice develop tumors by 22 weeks of age and die prematurely




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory