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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Srcin1+
wild type
MGI:2436451
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Srcin1tm1.1(KOMP)Vlcg/Srcin1+ C57BL/6N-Srcin1tm1.1(KOMP)Vlcg/J MGI:5797847
ht2
 		Srcin1tm1Fdc/Srcin1+ Not Specified MGI:5689865


Genotype
MGI:5797847
ht1
Allelic
Composition		 Srcin1tm1.1(KOMP)Vlcg/Srcin1+
Genetic
Background		 C57BL/6N-Srcin1tm1.1(KOMP)Vlcg/J
Cell Lines 19023A-F10
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srcin1tm1.1(KOMP)Vlcg mutation (1 available); any Srcin1 mutation (52 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system

growth/size/body
increased heart weight ( J:211773 )
IMPC - JAX

skeleton




Genotype
MGI:5689865
ht2
Allelic
Composition		 Srcin1tm1Fdc/Srcin1+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srcin1tm1Fdc mutation (0 available); any Srcin1 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal dendritic spine morphology ( J:206962 )
• in culture, primary hippocampal neurons obtained from heterozygous embryos display a normal density of mushroom spines but show a significant increase in filopodial-like spines relative to wild-type neurons




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory