All Phenotypes Ywhaz<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ywhaz⁺
wild type
MGI:2434425

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Ywhaz^{tm1b(EUCOMM)Hmgu}/Ywhaz⁺	C57BL/6N-Ywhaz^{tm1b(EUCOMM)Hmgu}/Tcp	MGI:5757900
cn2	Ywhae^tm2.1Awb/Ywhae⁺ Ywhaz^{Gt(OST432062)Lex}/Ywhaz⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ Tg(Wnt1-GAL4)11Rth/0	involves: 129S6/SvEvTac * C57BL/6J	MGI:6267030
cn3	Ywhae^tm2.1Awb/Ywhae^tm2.1Awb Ywhaz^{Gt(OST432062)Lex}/Ywhaz⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ Tg(Wnt1-GAL4)11Rth/0	involves: 129S6/SvEvTac * C57BL/6J	MGI:6267035

Allelic Composition	Ywhaz^{tm1b(EUCOMM)Hmgu}/Ywhaz⁺
Genetic Background	C57BL/6N-Ywhaz^{tm1b(EUCOMM)Hmgu}/Tcp
Cell Lines	HEPD0716_9_A11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ywhaz^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Ywhaz mutation (32 available)

Data Sources

IMPC Data for Ywhaz

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal sinus arrhythmia ( J:211773 )

IMPC - TCP

hematopoietic system

increased leukocyte cell number ( J:211773 )

IMPC - TCP

increased lymphocyte cell number ( J:211773 )

IMPC - TCP

homeostasis/metabolism

edema ( J:211773 )

IMPC - TCP

immune system

increased leukocyte cell number ( J:211773 )

IMPC - TCP

increased lymphocyte cell number ( J:211773 )

IMPC - TCP

enlarged lymph nodes ( J:211773 )

IMPC - TCP

integument

abnormal skin morphology ( J:211773 )

IMPC - TCP

limbs/digits/tail

short tibia ( J:211773 )

IMPC - TCP

skeleton

short tibia ( J:211773 )

IMPC - TCP

vision/eye

abnormal retina morphology ( J:211773 )

IMPC - TCP

Allelic Composition	Ywhae^tm2.1Awb/Ywhae⁺ Ywhaz^{Gt(OST432062)Lex}/Ywhaz⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ Tg(Wnt1-GAL4)11Rth/0
Genetic Background	involves: 129S6/SvEvTac * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2az2^{Tg(Wnt1-cre)11Rth} mutation (2 available); any H2az2 mutation (25 available)
Tg(Wnt1-GAL4)11Rth mutation (2 available)
Ywhae^tm2.1Awb mutation (1 available); any Ywhae mutation (60 available)
Ywhaz^{Gt(OST432062)Lex} mutation (3 available); any Ywhaz mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

belly spot ( J:242528 )

• at P21, 88.5 % of mice show white patches of fur on the ventral region of their torso; the area of white patches is 0.69 cm²

• however, no white patches were observed on the tail and paws or any other region

integument

belly spot ( J:242528 )

• at P21, 88.5 % of mice show white patches of fur on the ventral region of their torso; the area of white patches is 0.69 cm²

• however, no white patches were observed on the tail and paws or any other region

Allelic Composition	Ywhae^tm2.1Awb/Ywhae^tm2.1Awb Ywhaz^{Gt(OST432062)Lex}/Ywhaz⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ Tg(Wnt1-GAL4)11Rth/0
Genetic Background	involves: 129S6/SvEvTac * C57BL/6J

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

belly spot ( J:242528 )

• at P21, 100% of mice show white patches of fur on the ventral region of their torso; the area of white patches is 0.97 cm²

• however, no white patches were observed on the tail and paws or any other region

integument

belly spot ( J:242528 )

• at P21, 100% of mice show white patches of fur on the ventral region of their torso; the area of white patches is 0.97 cm²

• however, no white patches were observed on the tail and paws or any other region

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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