Analysis Tools|
Allele Symbol Allele Name Allele ID |
Ackr3+ wild type MGI:2434403 |
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| Summary |
3 genotypes
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Data Sources
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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IMPC - ICS
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IMPC - ICS
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IMPC - ICS
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• a third of females have fibrosis and myocardial degeneration
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• a third of females have cardiac fibrosis and myocardial degeneration
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• peri-arteritis of the vasculature is found in a small subset of mice
• endothelial cells in these vessels are degenerated and areas of fibrosis surrounded these vessels
• alveolar macrophages had accumulated around these damaged vessels
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• peri-arteritis of the vasculature is found in a small subset of mice
• endothelial cells in these vessels are degenerated and areas of fibrosis surrounded these vessels
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• a third of females have fibrosis and myocardial degeneration
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• peri-arteritis of the vasculature is found in a small subset of mice
• endothelial cells in these vessels are degenerated and areas of fibrosis surrounded these vessels
• alveolar macrophages had accumulated around these damaged vessels
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• 10% of mice exhibit aortic valve leaflets that are thickened and/or fused with clear evidence of chondrification
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 01/28/2026 MGI 6.24 |
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