All Phenotypes Pkn2<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pkn2⁺
wild type
MGI:2434284

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Pkn2^{tm1b(KOMP)Wtsi}/Pkn2⁺	C57BL/6N-Pkn2^{tm1b(KOMP)Wtsi}/Ieg	MGI:6263174
cx2	Pkn1^tm1Ajmc/Pkn1^tm1Ajmc Pkn2^{tm1a(KOMP)Wtsi}/Pkn2⁺ Pkn3^tm1Ajmc/Pkn3^tm1Ajmc	involves: 129P2/OlaHsd * C57BL/6N * C57BL/6NTac	MGI:5912007

Allelic Composition	Pkn2^{tm1b(KOMP)Wtsi}/Pkn2⁺
Genetic Background	C57BL/6N-Pkn2^{tm1b(KOMP)Wtsi}/Ieg
Cell Lines	EPD0319_7_G05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkn2^{tm1b(KOMP)Wtsi} mutation (1 available); any Pkn2 mutation (84 available)

Data Sources

IMPC Data for Pkn2

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - HMGU

increased startle reflex ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

IMPC - HMGU

decreased circulating cholesterol level ( J:211773 )

IMPC - HMGU

decreased circulating HDL cholesterol level ( J:211773 )

IMPC - HMGU

decreased circulating total protein level ( J:211773 )

IMPC - HMGU

decreased circulating unsaturated transferrin level ( J:211773 )

IMPC - HMGU

Allelic Composition	Pkn1^tm1Ajmc/Pkn1^tm1Ajmc Pkn2^{tm1a(KOMP)Wtsi}/Pkn2⁺ Pkn3^tm1Ajmc/Pkn3^tm1Ajmc
Genetic Background	involves: 129P2/OlaHsd * C57BL/6N * C57BL/6NTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkn1^tm1Ajmc mutation (0 available); any Pkn1 mutation (47 available)
Pkn2^{tm1a(KOMP)Wtsi} mutation (1 available); any Pkn2 mutation (84 available)
Pkn3^tm1Ajmc mutation (0 available); any Pkn3 mutation (55 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:229595 )

• viable and fertile with no overt phenotype

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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