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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dab1+
wild type
MGI:2434177
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Dab1tm1Bwh/Dab1+ involves: 129S4/SvJaeSor * C57BL/6 MGI:3810277
cn2
 		Dab1tm1Cpr/Dab1+
Rnf7tm1c(EUCOMM)Wtsi/Rnf7tm1c(EUCOMM)Wtsi
Tg(Nes-cre)1Kln/0 		involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * SJL MGI:5545907
cx3
 		Crmp1tm1Pako/Crmp1tm1Pako
Dab1yot/Dab1+ 		involves: 129/Sv * ICR MGI:3703439


Genotype
MGI:3810277
ht1
Allelic
Composition		 Dab1tm1Bwh/Dab1+
Genetic
Background		 involves: 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dab1tm1Bwh mutation (0 available); any Dab1 mutation (77 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal cerebellar foliation ( J:132599 )
• foliation is not as severely affected as in homozygous mice
small cerebellum ( J:132599 )
• cerebellar size is not as reduced as in homozygous mice




Genotype
MGI:5545907
cn2
Allelic
Composition		 Dab1tm1Cpr/Dab1+
Rnf7tm1c(EUCOMM)Wtsi/Rnf7tm1c(EUCOMM)Wtsi
Tg(Nes-cre)1Kln/0
Genetic
Background		 involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dab1tm1Cpr mutation (1 available); any Dab1 mutation (77 available)
Rnf7tm1c(EUCOMM)Wtsi mutation (0 available); any Rnf7 mutation (15 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:205551 )
N
• Purkinje cell positioning and cerebellum size are rescued compared to in Rnf7tm1c(EUCOMM)Wtsi/Rnf7tm1c(EUCOMM)Wtsi Tg(Nes-cre)1Kln mice




Genotype
MGI:3703439
cx3
Allelic
Composition		 Crmp1tm1Pako/Crmp1tm1Pako
Dab1yot/Dab1+
Genetic
Background		 involves: 129/Sv * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crmp1tm1Pako mutation (2 available); any Crmp1 mutation (45 available)
Dab1yot mutation (1 available); any Dab1 mutation (77 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal hippocampus layer morphology ( J:116689 )
• disrupted hippocampal lamination revealed by Nissl staining in P10 mutant brain




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory