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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Runx1t1+
wild type
MGI:2433290
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Runx1t1tm1b(EUCOMM)Hmgu/Runx1t1+ C57BL/6N-Runx1t1tm1b(EUCOMM)Hmgu/H MGI:6408634
ht2
 		Runx1t1tm1Fc/Runx1t1+ involves: 129S/SvEv * C57BL/6 MGI:3851363
cn3
 		Runx1t1tm1Buch/Runx1t1+
Runx1tm1Buch/Runx1+
Tg(Nes-cre)1Atp/0 		involves: FVB/N MGI:2671931


Genotype
MGI:6408634
ht1
Allelic
Composition		 Runx1t1tm1b(EUCOMM)Hmgu/Runx1t1+
Genetic
Background		 C57BL/6N-Runx1t1tm1b(EUCOMM)Hmgu/H
Cell Lines HEPD0697_3_E08
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Runx1t1tm1b(EUCOMM)Hmgu mutation (1 available); any Runx1t1 mutation (35 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism




Genotype
MGI:3851363
ht2
Allelic
Composition		 Runx1t1tm1Fc/Runx1t1+
Genetic
Background		 involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Runx1t1tm1Fc mutation (0 available); any Runx1t1 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
absent midgut ( J:70590 )
• ~1.3% of heterozygotes show an absence of the midgut, not observed in wild-type control littermates




Genotype
MGI:2671931
cn3
Allelic
Composition		 Runx1t1tm1Buch/Runx1t1+
Runx1tm1Buch/Runx1+
Tg(Nes-cre)1Atp/0
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Runx1t1tm1Buch mutation (0 available); any Runx1t1 mutation (35 available)
Runx1tm1Buch mutation (0 available); any Runx1 mutation (34 available)
Tg(Nes-cre)1Atp mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:68499 )
• mice were viable and showed no malignancies within 5 months of birth




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory