Phenotypes associated with this allele

• Allele Symbol: Vcan⁺
• Allele Name: wild type
• Allele ID: MGI:2433022
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Vcan^em2(IMPC)Mbp/Vcan^+	C57BL/6NCrl-Vcan^em2(IMPC)Mbp/Mmucd	MGI:7596572
cx2	Adamts9^tm1Dgen/Adamts9^tm1Dgen Vcan^Tg(Hoxa1)1Chm/Vcan^+	B6.Cg-Adamts9^tm1Dgen Vcan^Tg(Hoxa1)1Chm	MGI:4418862

Genotype
MGI:7596572

ht1

• Allelic Composition: Vcan^em2(IMPC)Mbp/Vcan⁺
• Genetic Background: C57BL/6NCrl-Vcan^em2(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Vcan

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - UCD

eye hemorrhage ( J:211773 )

♀

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

growth/size/body

enlarged spleen ( J:211773 )

♀

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

vision/eye

eye hemorrhage ( J:211773 )

♀

IMPC - UCD

abnormal eye morphology ( J:211773 )

♀

IMPC - UCD

persistence of hyaloid vascular system ( J:211773 )

IMPC - UCD

microphthalmia ( J:211773 )

IMPC - UCD

abnormal retina morphology ( J:211773 )

IMPC - UCD

Genotype
MGI:4418862

cx2

• Allelic Composition: Adamts9^tm1Dgen/Adamts9^tm1Dgen; Vcan^{Tg(Hoxa1)1Chm}/Vcan⁺
• Genetic Background: B6.Cg-Adamts9^tm1Dgen Vcan^{Tg(Hoxa1)1Chm}

limbs/digits/tail

syndactyly ( J:155754 )

• 100% penetrance of soft-tissue syndactyly (STS)

interdigital webbing ( J:155754 )