Phenotypes associated with this allele

• Allele Symbol: Tek⁺
• Allele Name: wild type
• Allele ID: MGI:2432156
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Tek^tm1b(EUCOMM)Hmgu/Tek^+	C57BL/6N-Tek^tm1b(EUCOMM)Hmgu/BayMmucd	MGI:6480607
cx2	Tek^tm1Dmt/Tek^+ Tie1^tm1Jpa/Tie1^tm1Jpa	involves: 129S1/Sv * 129X1/SvJ * CD-1	MGI:3851554

Genotype
MGI:6480607

ht1

• Allelic Composition: Tek^{tm1b(EUCOMM)Hmgu}/Tek⁺
• Genetic Background: C57BL/6N-Tek^{tm1b(EUCOMM)Hmgu}/BayMmucd
• Cell Lines: HEPD0646_3_C05

Data Sources

IMPC Data for Tek

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - BCM

Genotype
MGI:3851554

cx2

• Allelic Composition: Tek^tm1Dmt/Tek⁺; Tie1^tm1Jpa/Tie1^tm1Jpa
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:54983 )

• mice die by E10.5

cardiovascular system

abnormal cardiovascular development ( J:54983 )

• at E9.5

abnormal vascular development ( J:54983 )

• maintenance of blood vessels in the head and extremities is poor

abnormal heart development ( J:54983 )

• atrial and ventricular endocardium is poorly maintained

enlarged pericardium ( J:54983 )

hemorrhage ( J:54983 )

heart hemorrhage ( J:54983 )

congestive heart failure ( J:54983 )

homeostasis/metabolism

edema ( J:54983 )