Analysis Tools|
Allele Symbol Allele Name Allele ID |
Prlr+ wild type MGI:2431869 |
||||||||||||||||||||||||
| Summary |
5 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• at gestation day 7, mated females exhibit less of an increase in forebrain neurogenesis compared with mated wild-type mice
|
|
• at gestation day 7, mated females exhibit less of an increase in forebrain neurogenesis compared with mated wild-type mice
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
 |
• some mothers scattered their pups, often burying them in sawdust
|
|
|
• when the mother reformed the nest, a pup was often left outside and not retrieved, whereas the others were suckled
|
|
|
• impaired development after first, but not subsequent, pregnancies
|
|
|
• failure of lactation attributable after first, but not subsequent, pregancies
|
|
|
• impaired development after first, but not subsequent, pregnancies
|
|
|
• failure of lactation attributable after first, but not subsequent, pregancies
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal spatial learning in a Morris water maze test
|
|
|
• virgin female require 4 days to develop full maternal behavior towards fostered pups compared with 1 or 2 days for wild-type mice
|
|
|
• virgin females take 4 to 5 days of daily exposure sessions to fostered pups to retrieve them compared with 1 or 2 daily exposure sessions for wild-type mice
|
| N |
• mice exhibit normal olfaction
|
|
• intermediate timing of molting relative to homozygotes and wild-type mice
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
|
• at 2 days postpartum, lobuloalveolar structures are underdeveloped compared to in wild-type mice
|
|
|
• at 2 days postpartum, lobuloalveolar structures are underdeveloped compared to in wild-type mice
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• unlike in Prlrtm1Cnp heterozygotes, lobuloalveolar structure development at 2 days postpartum is normal
|
| N |
• unlike in Prlrtm1Cnp heterozygotes, lobuloalveolar structure development at 2 days postpartum is normal
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 01/06/2026 MGI 6.24 |
|
|
|
||
